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How a Virus Stops Plant Defenses to Boost Immune Response
Greg Howard
18th July, 2024
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Image Source: Natural Science News, 2024
Key Findings
- The study from Nanjing Agricultural University focuses on the tomato NLR protein Sw-5b and its role in plant immunity
- In the absence of pathogens, Sw-5b is tagged for degradation by the E3 ligase SBP1, keeping its levels low
- During infection, the viral effector NSm disrupts this tagging, stabilizing Sw-5b and triggering a strong immune response
References
Main Study
1) A viral effector blocks the turnover of a plant NLR receptor to trigger a robust immune response.
Published 17th July, 2024
https://doi.org/10.1038/s44318-024-00174-6
Related Studies
2) Comparative Analysis of the Flax Immune Receptors L6 and L7 Suggests an Equilibrium-Based Switch Activation Model.
3) Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1.
4) Innate immunity in plants: an arms race between pattern recognition receptors in plants and effectors in microbial pathogens.