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Comparing a Single Dose of Two Boswellia Supplements in Healthy Volunteers
Jenn Hoskins
22nd July, 2024
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Image Source: Natural Science News, 2024
Key Findings
- Researchers at Ulm University found that a micellar formulation of Boswellia serrata significantly increased the bioavailability of its active compounds compared to a native formulation
- The micellar extract improved the absorption of boswellic and lupeolic acids by 1,720-4,291%, with acetyl-11-keto-β-boswellic acid (AKBA) showing the highest increase
- Despite the higher bioavailability, both the micellar and native formulations showed similar anti-inflammatory effects, reducing the release of the proinflammatory cytokine TNF-α
References
Main Study
1) Single-dose comparative pharmacokinetic/pharmacodynamic study of a micellar formulation versus a native Boswellia serrata dry extract in healthy volunteers.
Published 20th July, 2024
https://doi.org/10.1016/j.phymed.2024.155863
Related Studies
2) Boswellia serrata: an overall assessment of in vitro, preclinical, pharmacokinetic and clinical data.
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