Exploring Heart Health Benefits of Hibiscus and Herbal Mixes

Jenn Hoskins
16th January, 2024

Exploring Heart Health Benefits of Hibiscus and Herbal Mixes
Image Source: © Natural Science News. This image is an artistic rendition.
Hypertension, or high blood pressure, is a major health concern globally, contributing significantly to illness and death. Traditional medications for managing hypertension can be effective, but often come with unwanted side effects, particularly with long-term use[2]. This has led to growing interest in natural alternatives, with herbal remedies gaining popularity. Researchers at the National Research Centre, Egypt, recently investigated a blend of four herbs – Hibiscus, Corn silk, Marjoram, and Chamomile – to see if it could help lower blood pressure and improve cardiovascular health[1]. The study aimed to determine if an extract made from these plants could counteract the negative effects of induced hypertension in rats. The researchers first analyzed the herbal mixture to identify its key chemical components, finding a high concentration of flavonoids. Flavonoids are naturally occurring compounds found in many plants, known for their potential health benefits, including antioxidant and cardio-protective properties[3]. These compounds are thought to contribute to the positive effects observed with plant-based remedies. Before testing the mixture’s effectiveness, a safety assessment was conducted on female rats to determine appropriate dosages. Hypertension was then induced in both ovariectomized (ovaries removed) and non-ovariectomized rats using a chemical called L-Name. This chemical causes blood pressure to rise, mimicking the condition of hypertension. The rats were then divided into several groups: untreated hypertensive rats, and hypertensive rats treated with either a low dose, high dose of the herbal mixture, or a standard blood pressure medication (an angiotensin-converting enzyme inhibitor). The untreated hypertensive rats showed a range of negative health changes, including increased blood pressure, heart rate, cholesterol, and triglycerides. They also exhibited signs of inflammation and oxidative stress, indicated by elevated levels of malondialdehyde and C-reactive protein, alongside reduced levels of protective substances like glutathione and endothelial nitric oxide synthase. Importantly, treatment with the herbal mixture significantly reversed these negative effects. Both the low and high doses of the herbal blend helped to lower blood pressure and heart rate, improve cholesterol levels, and reduce inflammation and oxidative stress. The results were comparable to those seen with the standard blood pressure medication. This study builds on previous research demonstrating the potential of individual herbs to manage hypertension. For example, studies have shown that sour tea made from Hibiscus sabdariffa can effectively lower blood pressure in people with stage one hypertension[2]. The inclusion of marjoram in this new herbal mixture is also noteworthy, as aromatherapy using sweet marjoram essential oil has been shown to reduce both blood pressure and heart rate[4]. By combining these herbs, the researchers aimed to create a synergistic effect, maximizing the cardiovascular benefits. The researchers suggest that the herbal mixture’s effectiveness is likely due to its high flavonoid content. Flavonoids are known to protect blood vessels, reduce inflammation, and improve blood flow, all of which contribute to healthy blood pressure regulation[3]. The study indicates that this herbal mixture could be a promising natural supplement for supporting cardiovascular health.

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References

Main Study

1) A pharmacological and toxicological biochemical study of cardiovascular regulatory effects of hibiscus, corn silk, marjoram, and chamomile.

Published 15th January, 2024

https://doi.org/10.1016/j.heliyon.2023.e22659


Related Studies

2) Effect of hibiscus sabdariffa on blood pressure in patients with stage 1 hypertension.

https://doi.org/10.4103/japtr.JAPTR_402_18


3) Important Flavonoids and Their Role as a Therapeutic Agent.

https://doi.org/10.3390/molecules25225243


4) A novel approach for evaluating the effects of odor stimulation on dynamic cardiorespiratory functions.

https://doi.org/10.1371/journal.pone.0172841



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