Light-driven Creation of Custom-sized Silver Nanoparticles Using Yeast Extract

Greg Howard
15th July, 2024

Light-driven Creation of Custom-sized Silver Nanoparticles Using Yeast Extract

Image Source: Natural Science News, 2024

Key Findings

  • The study by MCI focused on the biosynthesis of silver nanoparticles (Ag-NPs) using Saccharomyces cerevisiae DSM 1333 and visible light
  • Using visible light, specifically white light, significantly increased the yield of Ag-NPs by more than 90%
  • The size of the Ag-NPs was controlled by light intensity, with particle sizes reducing from 130 nm to 100 nm as light intensity increased
The bio-based production of silver nanoparticles (Ag-NPs) offers a sustainable alternative to conventional physicochemical manufacturing methods. This approach not only reduces environmental impact but also yields nanoparticles with desirable properties such as narrow size dispersity, high stability, and biocompatibility. The study conducted by MCI investigated the biosynthesis of size-tuned silver nanoparticles using cell-free extracts of Saccharomyces cerevisiae DSM 1333[1]. This research aimed to optimize various parameters to control nanoparticle size and yield, utilizing visible light as a novel tool in the production process. Nanoparticles, particularly those made of silver, have broad applications due to their unique properties. For instance, Ag-NPs are known for their antimicrobial activity, making them valuable in food processing and packaging to ensure food safety[2]. Additionally, Ag-NPs are used in biosensors and medical imaging due to their high thermal and electrical conductivities and efficient electron transfer capabilities[3]. In this study, the researchers focused on optimizing single parameters during the phases of cultivation, extraction, and synthesis to achieve controlled nanoparticle size and increased yield. One of the significant innovations was the use of visible light, specifically white light, to influence nanoparticle production. The researchers employed novel LED systems to expose the reaction mixtures to varying intensities of white light, while control experiments were performed in the dark to compare the outcomes. The characterization of the resulting nanoparticles was carried out using several techniques, including spectrophotometric analysis, dynamic light scattering, scanning electron microscopy, and energy dispersive X-ray spectroscopy. These methods revealed that the biosynthesized silver nanoparticles were spherical with controlled, light-mediated size shifts and were produced in significantly increased quantities. Specifically, the nanoparticle yields increased by more than 90% when irradiated at 1.0±0.2 mWcm⁻². Moreover, the particle dimensions were reduced, with size-specific absorption maxima shifting from 440 nm to 410 nm, corresponding to particle sizes of 130 nm and 100 nm, respectively. The use of white light emerged as an excellent tool for nano-manufacturing, demonstrating advantageous effects for modulating unique particle properties. This finding aligns with previous research that highlighted the importance of environmentally friendly nanoparticle synthesis methods[4]. By leveraging biological processes, such as those involving microorganisms like Saccharomyces cerevisiae, researchers can produce nanoparticles without generating toxic waste, thus promoting a green synthesis approach. The potential applications of these biosynthesized silver nanoparticles are vast. In the food industry, for example, Ag-NPs can be used to develop safer and contamination-free food products, enhancing food safety and extending shelf life[5]. Additionally, their antimicrobial properties make them suitable for use in various medical and environmental applications[3]. In summary, the study conducted by MCI demonstrates that the biosynthesis of silver nanoparticles using Saccharomyces cerevisiae and visible light is a promising approach for producing high-quality nanomaterials. The optimization of synthesis parameters and the innovative use of light irradiation not only improve yield but also allow for precise control over nanoparticle size. This method represents a significant advancement in the field of nanotechnology, offering sustainable and efficient solutions for various industrial and scientific applications.

BiotechBiochemMycology

References

Main Study

1) Light-mediated biosynthesis of size-tuned silver nanoparticles using Saccharomyces cerevisiae extract

Published 14th July, 2024

https://doi.org/10.1007/s00449-024-03060-x

Related Studies

2) Silver Nanoparticles against Foodborne Bacteria. Effects at Intestinal Level and Health Limitations.

https://doi.org/10.3390/microorganisms8010132

3) Silver nanoparticle in biosensor and bioimaging: Clinical perspectives.

https://doi.org/10.1002/bab.2045

4) Microorganisms as efficient biosystem for the synthesis of metal nanoparticles: current scenario and future possibilities.

https://doi.org/10.1007/s11274-016-2044-1

5) Application of Nanotechnology in Food Science: Perception and Overview.

https://doi.org/10.3389/fmicb.2017.01501


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