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PUB40 Reduces Plant Resistance by Disrupting Key Defense Pathways
Jim Crocker
28th June, 2024
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Image Source: Natural Science News, 2024
Key Findings
- Researchers at China Agricultural University studied the role of the MEK2-SIPK/WIPK cascade in plant immunity in Nicotiana benthamiana
- They found that the NbPUB40 protein negatively regulates plant defense by promoting the degradation of the MEK2-SIPK/WIPK proteins
- Knockdown mutants of NbPUB40 showed increased resistance to the pathogen Phytophthora capsici, indicating NbPUB40's role in weakening plant immunity
References
Main Study
1) PUB40 attenuates Phytophthora capsici resistance by destabilizing the MEK2-SIPK/WIPK cascade in Nicotiana benthamiana
Published 27th June, 2024
https://doi.org/10.1186/s42483-024-00249-6
Related Studies
2) MAP kinase signalling cascade in Arabidopsis innate immunity.
Journal: Nature, Issue: Vol 415, Issue 6875, Feb 2002
3) MAPK signaling regulates nitric oxide and NADPH oxidase-dependent oxidative bursts in Nicotiana benthamiana.
4) Phytophthora infestans effector AVR3a is essential for virulence and manipulates plant immunity by stabilizing host E3 ligase CMPG1.